Human butyrylcholinesterase in Cohn fraction IV-4 purified in a single chromatography step on Hupresin

Protection from the toxicity of nerve agents is achieved by pretreatment with human butyrylcholinesterase (BChE). Current methods for purifying large quantities of BChE from frozen Cohn fraction IV-4 produce 99% pure enzyme, but the yield is low (21%). Our goal was to simplify the purification proce...

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Detalles Bibliográficos
Autores principales: M. Schopfer, Lawrence, David, Emilie, Hinrichs, Steven H., Lockridge, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838835/
https://www.ncbi.nlm.nih.gov/pubmed/36638134
http://dx.doi.org/10.1371/journal.pone.0280380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838835/
https://www.ncbi.nlm.nih.gov/pubmed/36638134
http://dx.doi.org/10.1371/journal.pone.0280380

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