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Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trial

BACKGROUND: Cardiac complications, including heart failure and arrhythmias, are the leading causes of disability and death in Chagas disease (CD). CD, caused by the Trypanosoma cruzi parasite, afflicts 7 million people in Latin America, and its incidence is increasing in non-endemic countries due to...

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Detalles Bibliográficos
Autores principales: Campos-Estrada, Carolina, Urarte, Edurne, Denegri, Marisol, Villalón, Litzi, González-Herrera, Fabiola, Kemmerling, Ulrike, Maya, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838836/
https://www.ncbi.nlm.nih.gov/pubmed/36638112
http://dx.doi.org/10.1371/journal.pone.0280335