SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

SHP-1 is a cytosolic tyrosine phosphatase that is primarily expressed in hematopoietic cells. It acts as a negative regulator of numerous signaling pathways and controls multiple cellular functions involved in cancer pathogenesis. This study describes the binding preferences of SHP-1 (pY536) to c-Sr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gul, Mehreen, Navid, Ahmad, Fakhar, Muhammad, Rashid, Sajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838854/
https://www.ncbi.nlm.nih.gov/pubmed/36638102
http://dx.doi.org/10.1371/journal.pone.0278448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838854/
https://www.ncbi.nlm.nih.gov/pubmed/36638102
http://dx.doi.org/10.1371/journal.pone.0278448

Ejemplares similares