Influenza A virus strain PR/8/34, but neither HAM/2009 nor WSN/33, is transiently inhibited by the PB2-targeting drug paliperidone

Influenza A virus (FLUAV) is a significant human pathogen. In silico structural analysis (PMID 28628827) has suggested that the FDA-approved drug paliperidone interferes with the binding of the FLUAV polymerase subunit PB2 to the nucleoprotein NP. We found that paliperidone inhibits FLUAV A/PR/8/34...

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Detalles Bibliográficos
Autores principales: Panagiotidis, Georgios-Dimitrios, Müller, Christin, Binder, Marco, Weber, Friedemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839214/
https://www.ncbi.nlm.nih.gov/pubmed/36637551
http://dx.doi.org/10.1007/s00705-022-05696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839214/
https://www.ncbi.nlm.nih.gov/pubmed/36637551
http://dx.doi.org/10.1007/s00705-022-05696-0

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