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Protein structure prediction has reached the single-structure frontier

Dramatic advances in protein structure prediction have sparked debate as to whether the problem of predicting structure from sequence is solved or not. Here, I argue that AlphaFold2 and its peers are currently limited by the fact that they predict only a single structure, instead of a structural dis...

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Detalles Bibliográficos
Autor principal: Lane, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839224/
https://www.ncbi.nlm.nih.gov/pubmed/36639584
http://dx.doi.org/10.1038/s41592-022-01760-4