The ERAD system is restricted by elevated ceramides

Misfolded proteins in the endoplasmic reticulum (ER) are removed through a process known as ER-associated degradation (ERAD). ERAD occurs through an integral membrane protein quality control system that recognizes substrates, retrotranslocates the substrates across the membrane, and ubiquitinates an...

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Detalles Bibliográficos
Autores principales: Hwang, Jiwon, Peterson, Brian G., Knupp, Jeffrey, Baldridge, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839339/
https://www.ncbi.nlm.nih.gov/pubmed/36638172
http://dx.doi.org/10.1126/sciadv.add8579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839339/
https://www.ncbi.nlm.nih.gov/pubmed/36638172
http://dx.doi.org/10.1126/sciadv.add8579

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