Cargando…

FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF Pathways

Osteoclast (OC) abnormalities lead to many osteolytic diseases, such as osteoporosis, inflammatory bone erosion, and tumor-induced osteolysis. Exploring effective strategies to remediate OCs dysregulation is essential. FTY720, also known as fingolimod, has been approved for the treatment of multiple...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chongwei, Zong, Sujing, Wang, Zhenyu, Yang, Ruijia, Guo, Yanjing, Wang, Yunfei, Chen, Xinping, Li, Yue, Wang, Shaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839404/
https://www.ncbi.nlm.nih.gov/pubmed/36644540
http://dx.doi.org/10.1155/2023/8571649