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FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF Pathways
Osteoclast (OC) abnormalities lead to many osteolytic diseases, such as osteoporosis, inflammatory bone erosion, and tumor-induced osteolysis. Exploring effective strategies to remediate OCs dysregulation is essential. FTY720, also known as fingolimod, has been approved for the treatment of multiple...
Autores principales: | Chen, Chongwei, Zong, Sujing, Wang, Zhenyu, Yang, Ruijia, Guo, Yanjing, Wang, Yunfei, Chen, Xinping, Li, Yue, Wang, Shaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839404/ https://www.ncbi.nlm.nih.gov/pubmed/36644540 http://dx.doi.org/10.1155/2023/8571649 |
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