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Presence of cells in the polyaneuploid cancer cell (PACC) state predicts the risk of recurrence in prostate cancer
BACKGROUND: The nonproliferating polyaneuploid cancer cell (PACC) state is associated with therapeutic resistance in cancer. A subset of cancer cells enters the PACC state by polyploidization and acts as cancer stem cells by undergoing depolyploidization and repopulating the tumor cell population af...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839595/ https://www.ncbi.nlm.nih.gov/pubmed/36372998 http://dx.doi.org/10.1002/pros.24459 |