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Presence of cells in the polyaneuploid cancer cell (PACC) state predicts the risk of recurrence in prostate cancer

BACKGROUND: The nonproliferating polyaneuploid cancer cell (PACC) state is associated with therapeutic resistance in cancer. A subset of cancer cells enters the PACC state by polyploidization and acts as cancer stem cells by undergoing depolyploidization and repopulating the tumor cell population af...

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Detalles Bibliográficos
Autores principales: Trabzonlu, Levent, Pienta, Kenneth J., Trock, Bruce J., De Marzo, Angelo M., Amend, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839595/
https://www.ncbi.nlm.nih.gov/pubmed/36372998
http://dx.doi.org/10.1002/pros.24459