Cargando…
Presence of cells in the polyaneuploid cancer cell (PACC) state predicts the risk of recurrence in prostate cancer
BACKGROUND: The nonproliferating polyaneuploid cancer cell (PACC) state is associated with therapeutic resistance in cancer. A subset of cancer cells enters the PACC state by polyploidization and acts as cancer stem cells by undergoing depolyploidization and repopulating the tumor cell population af...
Autores principales: | Trabzonlu, Levent, Pienta, Kenneth J., Trock, Bruce J., De Marzo, Angelo M., Amend, Sarah R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839595/ https://www.ncbi.nlm.nih.gov/pubmed/36372998 http://dx.doi.org/10.1002/pros.24459 |
Ejemplares similares
-
Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential
por: Mallin, Mikaela M., et al.
Publicado: (2023) -
Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells
por: Pienta, K. J., et al.
Publicado: (2021) -
Lipid droplet evolution gives insight into polyaneuploid cancer cell lipid droplet functions
por: Kostecka, Laurie G., et al.
Publicado: (2021) -
A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells
por: Bukkuri, Anuraag, et al.
Publicado: (2022) -
A mathematical investigation of polyaneuploid cancer cell memory and cross-resistance in state-structured cancer populations
por: Bukkuri, Anuraag, et al.
Publicado: (2023)