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CD4(+) helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment
Despite their low abundance in the tumor microenvironment (TME), classical type 1 dendritic cells (cDC1) play a pivotal role in anti-cancer immunity, and their abundance positively correlates with patient survival. However, their interaction with CD4(+) T-cells to potentially enable the cytotoxic T...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839676/ https://www.ncbi.nlm.nih.gov/pubmed/36639382 http://dx.doi.org/10.1038/s41467-022-35615-5 |