CD4(+) helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment

Despite their low abundance in the tumor microenvironment (TME), classical type 1 dendritic cells (cDC1) play a pivotal role in anti-cancer immunity, and their abundance positively correlates with patient survival. However, their interaction with CD4(+) T-cells to potentially enable the cytotoxic T...

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Detalles Bibliográficos
Autores principales: Lei, Xin, Khatri, Indu, de Wit, Tom, de Rink, Iris, Nieuwland, Marja, Kerkhoven, Ron, van Eenennaam, Hans, Sun, Chong, Garg, Abhishek D., Borst, Jannie, Xiao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839676/
https://www.ncbi.nlm.nih.gov/pubmed/36639382
http://dx.doi.org/10.1038/s41467-022-35615-5

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