Gut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia

Familial dysautonomia (FD) is a rare genetic neurologic disorder caused by impaired neuronal development and progressive degeneration of both the peripheral and central nervous systems. FD is monogenic, with >99.4% of patients sharing an identical point mutation in the elongator acetyltransferase...

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Detalles Bibliográficos
Autores principales: Cheney, Alexandra M., Costello, Stephanann M., Pinkham, Nicholas V., Waldum, Annie, Broadaway, Susan C., Cotrina-Vidal, Maria, Mergy, Marc, Tripet, Brian, Kominsky, Douglas J., Grifka-Walk, Heather M., Kaufmann, Horacio, Norcliffe-Kaufmann, Lucy, Peach, Jesse T., Bothner, Brian, Lefcort, Frances, Copié, Valérie, Walk, Seth T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839693/
https://www.ncbi.nlm.nih.gov/pubmed/36639365
http://dx.doi.org/10.1038/s41467-023-35787-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839693/
https://www.ncbi.nlm.nih.gov/pubmed/36639365
http://dx.doi.org/10.1038/s41467-023-35787-8

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