Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells

Pancreatic-β-cell-specifying transcription factor Nkx6.1, indispensable for embryonic development of the pancreatic epithelium and commitment to β-cell lineage, directly controls the expression of a glucose transporter (Glut2), pyruvate carboxylase (Pcx), and genes for insulin processing (endoplasmi...

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Detalles Bibliográficos
Autores principales: Pavluch, Vojtěch, Engstová, Hana, Špačková, Jitka, Ježek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839711/
https://www.ncbi.nlm.nih.gov/pubmed/36639413
http://dx.doi.org/10.1038/s41598-023-27985-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839711/
https://www.ncbi.nlm.nih.gov/pubmed/36639413
http://dx.doi.org/10.1038/s41598-023-27985-7

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