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Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth

Tumor-associated macrophages (TAMs) account for 30–50% of glioma microenvironment. The interaction between glioma tumor cells and TAMs can promote tumor progression, but the intrinsic mechanisms remain unclear. Herein, we reported that soluble LRIG3 (sLRIG3) derived from glioma tumor cells can block...

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Detalles Bibliográficos
Autores principales: Li, Youwei, Wang, Wei, Hou, Xiaoshuang, Huang, Wenda, Zhang, Po, He, Yue, Wang, Baofeng, Duan, Qiuhong, Mao, Feng, Guo, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839712/
https://www.ncbi.nlm.nih.gov/pubmed/36639372
http://dx.doi.org/10.1038/s41419-023-05555-z