Cargando…

Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes

Imeglimin is a recently launched antidiabetic drug structurally related to metformin. To provide insight into the pharmacological properties of imeglimin, we investigated its effects on hepatocytes and compared them with those of metformin. The effects of imeglimin on mitochondrial function in HepG2...

Descripción completa

Detalles Bibliográficos
Autores principales: Hozumi, Kaori, Sugawara, Kenji, Ishihara, Takaya, Ishihara, Naotada, Ogawa, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839736/
https://www.ncbi.nlm.nih.gov/pubmed/36639407
http://dx.doi.org/10.1038/s41598-023-27689-y