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Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors

The proper regulation of muscle stem cell (MuSC) fate by cues from the niche is essential for regeneration of skeletal muscle. How pro-regenerative niche factors control the dynamics of MuSC fate decisions remains unknown due to limitations of population-level endpoint assays. To address this knowle...

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Detalles Bibliográficos
Autores principales: Togninalli, Matteo, Ho, Andrew T. V., Madl, Christopher M., Holbrook, Colin A., Wang, Yu Xin, Magnusson, Klas E. G., Kirillova, Anna, Chang, Andrew, Blau, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839750/
https://www.ncbi.nlm.nih.gov/pubmed/36639373
http://dx.doi.org/10.1038/s41536-023-00277-4