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Mass spectrometry analysis of gut tissue in acute SIV-infection in rhesus macaques identifies early proteome alterations preceding the interferon inflammatory response

HIV infection damages the gut mucosa leading to chronic immune activation, increased morbidities and mortality, and antiretroviral therapies, do not completely ameliorate mucosal dysfunction. Understanding early molecular changes in acute infection may identify new biomarkers underlying gut dysfunct...

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Detalles Bibliográficos
Autores principales: Berard, A. R., Hensley-McBain, T., Noël-Romas, L., Birse, K., Abou, M., Westmacott, G., McCorrister, S., Smedley, J., Klatt, Nichole R., Burgener, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839751/
https://www.ncbi.nlm.nih.gov/pubmed/36639424
http://dx.doi.org/10.1038/s41598-022-27112-y