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Stress promotes RNA G-quadruplex folding in human cells

Guanine (G)-rich nucleic acids can fold into G-quadruplex (G4) structures under permissive conditions. Although many RNAs contain sequences that fold into RNA G4s (rG4s) in vitro, their folding and functions in vivo are not well understood. In this report, we showed that the folding of putative rG4s...

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Detalles Bibliográficos
Autores principales: Kharel, Prakash, Fay, Marta, Manasova, Ekaterina V., Anderson, Paul J., Kurkin, Alexander V., Guo, Junjie U., Ivanov, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839774/
https://www.ncbi.nlm.nih.gov/pubmed/36639366
http://dx.doi.org/10.1038/s41467-023-35811-x