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Multiple pkd and piezo gene family members are required for atrioventricular valve formation

Cardiac valves ensure unidirectional blood flow through the heart, and altering their function can result in heart failure. Flow sensing via wall shear stress and wall stretching through the action of mechanosensors can modulate cardiac valve formation. However, the identity and precise role of the...

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Detalles Bibliográficos
Autores principales: Juan, Thomas, Ribeiro da Silva, Agatha, Cardoso, Bárbara, Lim, SoEun, Charteau, Violette, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839778/
https://www.ncbi.nlm.nih.gov/pubmed/36639367
http://dx.doi.org/10.1038/s41467-023-35843-3