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Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2

Guanylate-binding proteins (GBPs) are a group of GTPases that are induced by interferon-[Formula: see text] and are crucial components of cell-autonomous immunity against intracellular pathogens. Here, we examine murine GBP2 (mGBP2), which we have previously shown to be an essential effector protein...

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Detalles Bibliográficos
Autores principales: Loschwitz, Jennifer, Steffens, Nora, Wang, Xue, Schäffler, Moritz, Pfeffer, Klaus, Degrandi, Daniel, Strodel, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839784/
https://www.ncbi.nlm.nih.gov/pubmed/36639389
http://dx.doi.org/10.1038/s41598-023-27520-8