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Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth

BACKGROUND: The MYC oncoprotein, also known as the master regulator of genes, is a transcription factor that regulates numerous physiological processes, including cell cycle control, apoptosis, protein synthesis and cell adhesion, among others. MYC is overexpressed in approximately 70% of human canc...

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Detalles Bibliográficos
Autores principales: Xiong, Yan, Wang, Lulu, Xu, Shiyao, Fu, Beibei, Che, Yuchen, Zaky, Mohamed Y., Tian, Rong, Yao, Rui, Guo, Dong, Sha, Zhou, Lin, Feng, Lin, Xiaoyuan, Wu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839843/
https://www.ncbi.nlm.nih.gov/pubmed/36639831
http://dx.doi.org/10.1002/ctm2.1153