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Toxicogenomics Data for Chemical Safety Assessment and Development of New Approach Methodologies: An Adverse Outcome Pathway‐Based Approach

Mechanistic toxicology provides a powerful approach to inform on the safety of chemicals and the development of safe‐by‐design compounds. Although toxicogenomics supports mechanistic evaluation of chemical exposures, its implementation into the regulatory framework is hindered by uncertainties in th...

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Detalles Bibliográficos
Autores principales: Saarimäki, Laura Aliisa, Morikka, Jack, Pavel, Alisa, Korpilähde, Seela, del Giudice, Giusy, Federico, Antonio, Fratello, Michele, Serra, Angela, Greco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839874/
https://www.ncbi.nlm.nih.gov/pubmed/36479815
http://dx.doi.org/10.1002/advs.202203984