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Toxicogenomics Data for Chemical Safety Assessment and Development of New Approach Methodologies: An Adverse Outcome Pathway‐Based Approach
Mechanistic toxicology provides a powerful approach to inform on the safety of chemicals and the development of safe‐by‐design compounds. Although toxicogenomics supports mechanistic evaluation of chemical exposures, its implementation into the regulatory framework is hindered by uncertainties in th...
Autores principales: | Saarimäki, Laura Aliisa, Morikka, Jack, Pavel, Alisa, Korpilähde, Seela, del Giudice, Giusy, Federico, Antonio, Fratello, Michele, Serra, Angela, Greco, Dario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839874/ https://www.ncbi.nlm.nih.gov/pubmed/36479815 http://dx.doi.org/10.1002/advs.202203984 |
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