Modulating the expression of tumor suppressor genes using activating oligonucleotide technologies as a therapeutic approach in cancer

Tumor suppressor genes (TSGs) are frequently downregulated in cancer, leading to dysregulation of the pathways that they control. The continuum model of tumor suppression suggests that even subtle changes in TSG expression, for example, driven by epigenetic modifications or copy number alterations,...

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Detalles Bibliográficos
Autores principales: Gregory, Georgina L., Copple, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840112/
https://www.ncbi.nlm.nih.gov/pubmed/36700046
http://dx.doi.org/10.1016/j.omtn.2022.12.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840112/
https://www.ncbi.nlm.nih.gov/pubmed/36700046
http://dx.doi.org/10.1016/j.omtn.2022.12.016

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