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Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing

The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for generation of human dorsoventral spinal cord organoids...

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Detalles Bibliográficos
Autores principales: Xue, Weiwei, Li, Bo, Liu, Huihui, Xiao, Yujie, Ren, Lei, Li, Huijuan, Shao, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840144/
https://www.ncbi.nlm.nih.gov/pubmed/36647382
http://dx.doi.org/10.1016/j.isci.2022.105898