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Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing
The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for generation of human dorsoventral spinal cord organoids...
Autores principales: | Xue, Weiwei, Li, Bo, Liu, Huihui, Xiao, Yujie, Ren, Lei, Li, Huijuan, Shao, Zhicheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840144/ https://www.ncbi.nlm.nih.gov/pubmed/36647382 http://dx.doi.org/10.1016/j.isci.2022.105898 |
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