Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity

The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis (ORFV) and other OVs are thought to induce apoptosis, but apoptosis, being the immunogenically inert compared to other t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jing, Sun, Shihui, Zhao, Kui, Gao, Fei, Wang, Renling, Li, Qi, Zhou, Yanlong, Zhang, Jing, Li, Yue, Wang, Xinyue, Du, Le, Wang, Shuai, Li, Zi, Lu, Huijun, Lan, Yungang, Song, Deguang, Guo, Wei, Chen, Yujia, Gao, Feng, Zhao, Yicheng, Fan, Rongrong, Guan, Jiyu, He, Wenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840172/
https://www.ncbi.nlm.nih.gov/pubmed/36641456
http://dx.doi.org/10.1038/s41467-023-35917-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840172/
https://www.ncbi.nlm.nih.gov/pubmed/36641456
http://dx.doi.org/10.1038/s41467-023-35917-2

Ejemplares similares