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Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity

The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis (ORFV) and other OVs are thought to induce apoptosis, but apoptosis, being the immunogenically inert compared to other t...

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Detalles Bibliográficos
Autores principales:	Lin, Jing, Sun, Shihui, Zhao, Kui, Gao, Fei, Wang, Renling, Li, Qi, Zhou, Yanlong, Zhang, Jing, Li, Yue, Wang, Xinyue, Du, Le, Wang, Shuai, Li, Zi, Lu, Huijun, Lan, Yungang, Song, Deguang, Guo, Wei, Chen, Yujia, Gao, Feng, Zhao, Yicheng, Fan, Rongrong, Guan, Jiyu, He, Wenqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840172/ https://www.ncbi.nlm.nih.gov/pubmed/36641456 http://dx.doi.org/10.1038/s41467-023-35917-2

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