Sequential magnesium binding facilitates lysyl-tRNA synthetase to recognize ATP

Aminoacyl-tRNA synthetases (aaRSs) catalyze the ligation of amino acids to cognate tRNAs by consuming one molecule of ATP. Magnesium is essential for the enzymes’ activity. Certain class II aaRSs, such as lysyl-tRNA synthetase (LysRS) and seryl-tRNA synthetase (SerRS), recognize ATP together with th...

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Detalles Bibliográficos
Autores principales: Hei, Zhoufei, Fang, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840234/
https://www.ncbi.nlm.nih.gov/pubmed/36647555
http://dx.doi.org/10.1016/j.bbrep.2023.101426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840234/
https://www.ncbi.nlm.nih.gov/pubmed/36647555
http://dx.doi.org/10.1016/j.bbrep.2023.101426

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