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Tyrosine phosphatase STEP(61) in human dementia and in animal models with amyloid and tau pathology
Synaptic degeneration is a precursor of synaptic and neuronal loss in neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal dementia with tau pathology (FTD-tau), a group of primary tauopathies. A critical role in this degenerative process is assumed by enzymes such as the k...
Autores principales: | Taylor, Deonne, Kneynsberg, Andrew, van Roijen, Marloes, Götz, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840288/ https://www.ncbi.nlm.nih.gov/pubmed/36639708 http://dx.doi.org/10.1186/s13041-023-00994-3 |
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