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Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-Coenzyme A synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis

BACKGROUND: Glioblastoma is one of the malignant tumors of the central nervous system with high lethality, high disability and low survival rate. Effective induction of its death is one of the existing challenges. In recent studies, heat shock protein 27 (HSP27) has been shown to be associated with...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Wu, Yue, Chen, Guangliang, Wang, Hao, Liu, Yongsheng, Zhou, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840324/
https://www.ncbi.nlm.nih.gov/pubmed/36639654
http://dx.doi.org/10.1186/s12935-023-02848-3