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Dynamics of the gut microbiome, IgA response, and plasma metabolome in the development of pediatric celiac disease

BACKGROUND: Celiac disease (CD) is an autoimmune disorder triggered by gluten consumption. Almost all CD patients possess human leukocyte antigen (HLA) DQ2/DQ8 haplotypes; however, only a small subset of individuals carrying these alleles develop CD, indicating the role of environmental factors in C...

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Detalles Bibliográficos
Autores principales: Girdhar, Khyati, Dogru, Yusuf Dogus, Huang, Qian, Yang, Yi, Tolstikov, Vladimir, Raisingani, Amol, Chrudinova, Martina, Oh, Jaewon, Kelley, Kristina, Ludvigsson, Jonas F., Kiebish, Michael A., Palm, Noah W., Ludvigsson, Johnny, Altindis, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840338/
https://www.ncbi.nlm.nih.gov/pubmed/36639805
http://dx.doi.org/10.1186/s40168-022-01429-2