Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone

Nano-structured lipid carriers containing zopiclone were prepared as a targeted drug delivery system to convey zopiclone directly to brain via nasal route. Nano-structured lipid carriers were constructed adopting hot emulsification-ultrasonication method using palmitic acid in place of the solid lip...

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Autores principales:	Taha, Esraa, Nour, Samia A., Mamdouh, Wael, Selim, Adli A., Swidan, Mohamed M., Ibrahim, Ahmed B., Naguib, Marianne J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840360/ https://www.ncbi.nlm.nih.gov/pubmed/36647457 http://dx.doi.org/10.1016/j.ijpx.2023.100160