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Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone
Nano-structured lipid carriers containing zopiclone were prepared as a targeted drug delivery system to convey zopiclone directly to brain via nasal route. Nano-structured lipid carriers were constructed adopting hot emulsification-ultrasonication method using palmitic acid in place of the solid lip...
Autores principales: | Taha, Esraa, Nour, Samia A., Mamdouh, Wael, Selim, Adli A., Swidan, Mohamed M., Ibrahim, Ahmed B., Naguib, Marianne J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840360/ https://www.ncbi.nlm.nih.gov/pubmed/36647457 http://dx.doi.org/10.1016/j.ijpx.2023.100160 |
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