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In vitro and Intracellular Antibacterial Activity of Sudapyridine (WX-081) Against Tuberculosis

BACKGROUND: Sudapyridine (WX-081) has exhibited equivalent efficacy than its counterpart parent drug bedaquiline (BDQ) but better safety profile against Mycobacterium tuberculosis (Mtb). Our study was aimed to evaluate in vitro activity of WX-081 against the clinical isolates of Mtb with different d...

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Detalles Bibliográficos
Autores principales: Xiao, Hua, Yu, Xia, Shang, Yuanyuan, Ren, Ruyan, Xue, Yi, Dong, Lingling, Zhao, Liping, Jiang, Guanglu, Huang, Hairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840375/
https://www.ncbi.nlm.nih.gov/pubmed/36647451
http://dx.doi.org/10.2147/IDR.S390187