The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report

Acute lymphoblastic leukemia (ALL) is a group of hematological malignancies most commonly seen in pediatrics. The disease process localizes in lymphoid organs, the central nervous system, the mediastinum, and bone marrow (BM). The clinical features of T-cell acute lymphoblastic leukemia (T-ALL) in a...

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Autores principales: Motabi, Ibraheem H, Alsaif, Yara A, Bin Shuayl, Mohammed K, Farwana, Faisal M, Alhassan, Abdulaziz T, Alsaif, Faisal A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840415/
https://www.ncbi.nlm.nih.gov/pubmed/36655154
http://dx.doi.org/10.7759/cureus.33729
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author Motabi, Ibraheem H
Alsaif, Yara A
Bin Shuayl, Mohammed K
Farwana, Faisal M
Alhassan, Abdulaziz T
Alsaif, Faisal A
author_facet Motabi, Ibraheem H
Alsaif, Yara A
Bin Shuayl, Mohammed K
Farwana, Faisal M
Alhassan, Abdulaziz T
Alsaif, Faisal A
author_sort Motabi, Ibraheem H
collection PubMed
description Acute lymphoblastic leukemia (ALL) is a group of hematological malignancies most commonly seen in pediatrics. The disease process localizes in lymphoid organs, the central nervous system, the mediastinum, and bone marrow (BM). The clinical features of T-cell acute lymphoblastic leukemia (T-ALL) in adults include evidence of generalized lymphadenopathy, hepatosplenomegaly, immunosuppression, and hypercalcemia. There is limited research on the efficacy of using modified pediatric treatment regimens in the elderly over the age of 60 with ALL; this case report aims to illustrate the successful treatment of a 67-year-old male patient diagnosed with T-ALL, using a modified Children's Oncology Group (COG) protocol. Through this, it has been shown to be an effective, safe, and efficacious treatment option for our patient.
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spelling pubmed-98404152023-01-17 The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report Motabi, Ibraheem H Alsaif, Yara A Bin Shuayl, Mohammed K Farwana, Faisal M Alhassan, Abdulaziz T Alsaif, Faisal A Cureus Internal Medicine Acute lymphoblastic leukemia (ALL) is a group of hematological malignancies most commonly seen in pediatrics. The disease process localizes in lymphoid organs, the central nervous system, the mediastinum, and bone marrow (BM). The clinical features of T-cell acute lymphoblastic leukemia (T-ALL) in adults include evidence of generalized lymphadenopathy, hepatosplenomegaly, immunosuppression, and hypercalcemia. There is limited research on the efficacy of using modified pediatric treatment regimens in the elderly over the age of 60 with ALL; this case report aims to illustrate the successful treatment of a 67-year-old male patient diagnosed with T-ALL, using a modified Children's Oncology Group (COG) protocol. Through this, it has been shown to be an effective, safe, and efficacious treatment option for our patient. Cureus 2023-01-13 /pmc/articles/PMC9840415/ /pubmed/36655154 http://dx.doi.org/10.7759/cureus.33729 Text en Copyright © 2023, Motabi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Motabi, Ibraheem H
Alsaif, Yara A
Bin Shuayl, Mohammed K
Farwana, Faisal M
Alhassan, Abdulaziz T
Alsaif, Faisal A
The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title_full The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title_fullStr The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title_full_unstemmed The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title_short The Successful Implementation of a Modified Pediatric Acute Lymphoblastic Leukemia Protocol to Treat an Elderly Patient With T-cell Lymphoblastic Leukemia: A Case Report
title_sort successful implementation of a modified pediatric acute lymphoblastic leukemia protocol to treat an elderly patient with t-cell lymphoblastic leukemia: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840415/
https://www.ncbi.nlm.nih.gov/pubmed/36655154
http://dx.doi.org/10.7759/cureus.33729
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