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Simultaneous capture of ISG15 conjugating and deconjugating enzymes using a semi-synthetic ISG15-Dha probe

ISG15 is a ubiquitin-like (Ubl) protein attached to substrate proteins by ISG15 conjugating enzymes whose dysregulation is implicated in a multitude of disease processes, but the probing of these enzymes remains to be accomplished. Here, we describe the development of a new activity-based probe ISG1...

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Detalles Bibliográficos
Autores principales: Li, Chuntong, Wang, Tian, Liang, Lujun, Chu, Guochao, Zhang, Jiachen, He, Wei, Liu, Lei, Li, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840423/
https://www.ncbi.nlm.nih.gov/pubmed/36684644
http://dx.doi.org/10.1007/s11426-022-1455-x