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Synergistic prevention and reparative effects of sesquiterpene farnesol in a rabbit model of surgical resection-induced osteoarthritis

Articular cartilage may regenerate poorly after injury or during aging. In vitro, farnesol can modulate extracellular matrix synthesis and restore chondrocyte phenotypes by increasing type II collagen (COL II) and glycosaminoglycan (GAG) production. Here, we evaluated farnesol's preventive and...

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Detalles Bibliográficos
Autores principales: Chen, Chun Yu, Kuo, Shyh Ming, Wu, Guan Xuan, Yang, Shan Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840532/
https://www.ncbi.nlm.nih.gov/pubmed/36647547
http://dx.doi.org/10.1063/5.0129530