Cargando…
Fmr1-KO mice failure to detect object novelty associates with a post-test decrease of structural and synaptic plasticity upstream of the hippocampus
Mice with deletion of the FMR1 gene show episodic memory impairments and exhibit dendritic spines and synaptic plasticity defects prevalently identified in non-training conditions. Based on evidence that synaptic changes associated with normal or abnormal memory emerge when mice are cognitively chal...
Autores principales: | Borreca, Antonella, De Luca, Mariassunta, Ferrante, Antonella, Boussadia, Zaira, Pignataro, Annabella, Martire, Alberto, Ammassari-Teule, Martine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840621/ https://www.ncbi.nlm.nih.gov/pubmed/36641518 http://dx.doi.org/10.1038/s41598-023-27991-9 |
Ejemplares similares
-
Adenosine A(2A) receptor inhibition reduces synaptic and cognitive hippocampal alterations in Fmr1 KO mice
por: Ferrante, Antonella, et al.
Publicado: (2021) -
Indistinguishable pattern of amygdala and hippocampus rewiring following tone or contextual fear conditioning in C57BL/6 mice
por: Pignataro, Annabella, et al.
Publicado: (2013) -
CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex
por: Pignataro, Annabella, et al.
Publicado: (2015) -
Emotional remodeling with oxytocin durably rescues trauma-induced behavioral and neuro-morphological changes in rats: a promising treatment for PTSD
por: Le Dorze, Claire, et al.
Publicado: (2020) -
Reactivating fear memory under propranolol resets pre-trauma levels of dendritic spines in basolateral amygdala but not dorsal hippocampus neurons
por: Vetere, Gisella, et al.
Publicado: (2013)