Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity

Elimination of self-reactive T cells in the thymus is critical to establish T-cell tolerance. A growing body of evidence suggests a role for thymic B cells in the elimination of self-reactive thymocytes. To specifically address the role of thymic B cells in central tolerance, we investigated the phe...

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Detalles Bibliográficos
Autores principales: Lombard-Vadnais, Félix, Chabot-Roy, Geneviève, Zahn, Astrid, Rodriguez Torres, Sahily, Di Noia, Javier M., Melichar, Heather J., Lesage, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840937/
https://www.ncbi.nlm.nih.gov/pubmed/36654860
http://dx.doi.org/10.1016/j.isci.2022.105852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840937/
https://www.ncbi.nlm.nih.gov/pubmed/36654860
http://dx.doi.org/10.1016/j.isci.2022.105852

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