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Diptoindonesin G, a new Hsp90 drug

Hsp90 is a molecular chaperone that participates in protein folding, activation, and stabilization of substrate proteins. Since many diseases, including cancer, neurodegenerative diseases, and metabolic diseases, are caused by protein misfolding, drugs that inhibit Hsp90 are being pursued as potenti...

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Detalles Bibliográficos
Autores principales: Wickramaratne, Anushka, Wickner, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841029/
https://www.ncbi.nlm.nih.gov/pubmed/36572186
http://dx.doi.org/10.1016/j.jbc.2022.102826