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Diptoindonesin G, a new Hsp90 drug
Hsp90 is a molecular chaperone that participates in protein folding, activation, and stabilization of substrate proteins. Since many diseases, including cancer, neurodegenerative diseases, and metabolic diseases, are caused by protein misfolding, drugs that inhibit Hsp90 are being pursued as potenti...
Autores principales: | Wickramaratne, Anushka, Wickner, Sue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841029/ https://www.ncbi.nlm.nih.gov/pubmed/36572186 http://dx.doi.org/10.1016/j.jbc.2022.102826 |
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