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Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets

Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), are intimately associated with inflammation and overproduction of reactive oxygen species (ROS). Temporal and inter-individual variabilities in disease activity and response to therapy pose signifi...

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Detalles Bibliográficos
Autores principales: Bourgonje, Arno R., Kloska, Damian, Grochot-Przęczek, Anna, Feelisch, Martin, Cuadrado, Antonio, van Goor, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841059/
https://www.ncbi.nlm.nih.gov/pubmed/36634466
http://dx.doi.org/10.1016/j.redox.2023.102603