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Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases

The innate immune system protects the host from external pathogens and internal damage in various ways. The cGAS-STING signaling pathway, comprised of cyclic GMP-AMP synthase (cGAS), stimulator of interferon genes (STING), and downstream signaling adaptors, plays an essential role in protective immu...

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Detalles Bibliográficos
Autores principales: Pan, Jing, Fei, Chen-Jie, Hu, Yang, Wu, Xiang-Yu, Nie, Li, Chen, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841179/
https://www.ncbi.nlm.nih.gov/pubmed/36579404
http://dx.doi.org/10.24272/j.issn.2095-8137.2022.464