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The impact of early PEG-asparaginase discontinuation in young adults with ALL: a post hoc analysis of the CALGB 10403 study

Asparaginase is a key component of pediatric-inspired regimens in young adults with acute lymphoblastic leukemia (ALL). Truncation of asparaginase therapy is linked to inferior outcomes in children with ALL. However, a similar correlation in adults is lacking. Here, we studied the prevalence and ris...

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Detalles Bibliográficos
Autores principales: Aldoss, Ibrahim, Yin, Jun, Wall, Anna, Mrózek, Krzysztof, Liedtke, Michaela, Claxton, David F., Foster, Matthew C., Appelbaum, Frederick R., Erba, Harry P., Litzow, Mark R., Tallman, Martin S., Stone, Richard M., Larson, Richard A., Advani, Anjali S., Stock, Wendy, Luger, Selina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841239/
https://www.ncbi.nlm.nih.gov/pubmed/36269846
http://dx.doi.org/10.1182/bloodadvances.2022007791