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The impact of early PEG-asparaginase discontinuation in young adults with ALL: a post hoc analysis of the CALGB 10403 study
Asparaginase is a key component of pediatric-inspired regimens in young adults with acute lymphoblastic leukemia (ALL). Truncation of asparaginase therapy is linked to inferior outcomes in children with ALL. However, a similar correlation in adults is lacking. Here, we studied the prevalence and ris...
Autores principales: | Aldoss, Ibrahim, Yin, Jun, Wall, Anna, Mrózek, Krzysztof, Liedtke, Michaela, Claxton, David F., Foster, Matthew C., Appelbaum, Frederick R., Erba, Harry P., Litzow, Mark R., Tallman, Martin S., Stone, Richard M., Larson, Richard A., Advani, Anjali S., Stock, Wendy, Luger, Selina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841239/ https://www.ncbi.nlm.nih.gov/pubmed/36269846 http://dx.doi.org/10.1182/bloodadvances.2022007791 |
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