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Retromer oligomerization drives SNX‐BAR coat assembly and membrane constriction

Proteins exit from endosomes through tubular carriers coated by retromer, a complex that impacts cellular signaling, lysosomal biogenesis and numerous diseases. The coat must overcome membrane tension to form tubules. We explored the dynamics and driving force of this process by reconstituting coat...

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Detalles Bibliográficos
Autores principales: Gopaldass, Navin, De Leo, Maria Giovanna, Courtellemont, Thibault, Mercier, Vincent, Bissig, Christin, Roux, Aurélien, Mayer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841331/
https://www.ncbi.nlm.nih.gov/pubmed/36644906
http://dx.doi.org/10.15252/embj.2022112287