Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression

Numerous cancers, including prostate cancer (PCa), are addicted to transcription programs driven by specific genomic regions known as super-enhancers (SEs). The robust transcription of genes at such SEs is enabled by the formation of phase-separated condensates by transcription factors and coactivat...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Biswas, Maitree, Massah, Shabnam, Lee, Joseph, Lingadahalli, Shreyas, Wong, Samantha, Wells, Christopher, Foo, Jane, Khan, Nabeel, Morin, Helene, Saxena, Neetu, Kung, Sonia H Y, Sun, Bei, Parra Nuñez, Ana Karla, Sanchez, Christophe, Chan, Novia, Ung, Lauren, Altıntaş, Umut Berkay, Bui, Jennifer M, Wang, Yuzhuo, Fazli, Ladan, Oo, Htoo Zarni, Rennie, Paul S, Lack, Nathan A, Cherkasov, Artem, Gleave, Martin E, Gsponer, Jörg, Lallous, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841400/
https://www.ncbi.nlm.nih.gov/pubmed/36535377
http://dx.doi.org/10.1093/nar/gkac1158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841400/
https://www.ncbi.nlm.nih.gov/pubmed/36535377
http://dx.doi.org/10.1093/nar/gkac1158

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