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HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin

Nucleoli are nuclear compartments regulating ribosome biogenesis and cell growth. In embryonic stem cells (ESCs), nucleoli containing transcriptionally active ribosomal genes are spatially separated from pericentromeric satellite repeat sequences packaged in largely repressed constitutive heterochro...

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Detalles Bibliográficos
Autores principales: Ballmer, Daniel, Tardat, Mathieu, Ortiz, Raphael, Graff-Meyer, Alexandra, Ozonov, Evgeniy A, Genoud, Christel, Peters, Antoine HFM, Fanourgakis, Grigorios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841413/
https://www.ncbi.nlm.nih.gov/pubmed/36533441
http://dx.doi.org/10.1093/nar/gkac1159