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HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin
Nucleoli are nuclear compartments regulating ribosome biogenesis and cell growth. In embryonic stem cells (ESCs), nucleoli containing transcriptionally active ribosomal genes are spatially separated from pericentromeric satellite repeat sequences packaged in largely repressed constitutive heterochro...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841413/ https://www.ncbi.nlm.nih.gov/pubmed/36533441 http://dx.doi.org/10.1093/nar/gkac1159 |